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Have you tried lowering your dose? I only need 50 mg of moda in the morning to wake up and be productive.


Is it the undisputed champion of chess? I thought that A0 had never played Stockfish 10, the current best engine.


FYI earlier this month, they actually did announce the results of a 1000 game match:

https://www.chess.com/news/view/updated-alphazero-crushes-st....

AlphaZero won 155 games, lost 6, and drew 839 games against Stockfish. Granted, this was against Stockfish 9.

This implies that AlphaZero was roughly +52 Elo rating against Stockfish 9 (https://www.3dkingdoms.com/chess/elo.htm).

Stockfish 10 is currently rated ~32 points higher than Stockfish 9 (http://computerchess.org.uk/ccrl/4040/rating_list_all.html). If we were to do very crude transitive reasoning, you'd expect AlphaZero to still beat Stockfish 10.

EDIT:

So apparently the +155, -6 score was against Stockfish 8. Stockfish 8 is rated by the CCRL list at 3379, with Stockfish 10 rated 85 points stronger than 8.

Worth noting that AlphaZero was only given 4 out of 9 hours of total training time when playing against Stockfish 8 (https://chess24.com/en/read/news/alphazero-really-is-that-go...), but I guess we can't make any real conclusions about AlphaZero vs Stockfish 10.

EDIT 2:

So apparently AlphaZero also "defeated" Stockfish 9, but the preprint of the upcoming paper in Science doesn't seem to provide a crosstable.

It seems that Stockfish 8 was given a 44-core machine to play on, and was not constrained in terms of time spent per move etc.


Generally an "undisputed champion" title would require a level of effort that the AlphaZero team apparently isn't interested in. They like to run matches between AlphaZero and Stockfish in private under their own controlled conditions, and publish the results. The rest of the computer chess world likes to run tournaments in full public view, and there are several entities which run tournaments between engines that way which can be used to gauge the relative strength of the engines.

What will be interesting is to see the effect on Leela (https://github.com/LeelaChessZero/lczero), which is public and open-source, takes part in public tournaments, and is built -- as much as possible, based on what's been disclosed in the papers -- to use the same approach as AlphaZero.


Yeah, fair point. I didn't even think to challenge him on that. Technically it's not undisputed given that DeepMind hasn't made it available for any kind of "fair fight" organized outside of its own office. I'm guessing AlphaZero would still win, assuming DeepMind isn't literally faking data, but the only way to be sure is a match between A0 and SF 10.

FYI, Leela Chess Zero is the open-source project inspired by AlphaZero, and they recently did a match against SF 10, details here: https://lichess.org/blog/XA7juREAAC4AxZsR/deathmatch-leela-v...


Looks like the author posted it on his personal blog, but also on the group blog LessWrong, so the link avoided the filter.


The filter doesn't work several weeks later (or even days later AFAIK).

Also, the earlier submission didn't get a lot of comments (7) or votes, so a second run is probably OK by the guidelines.


>0.5g or 500mcg

I hope you mean 0.5 mg not 0.5g because that would be a very big dose!


I think he did mean .5mg since 500ug is .5mg. Still, I'm a bit confused. The bottles I get come in doses of 10mg, I can't imagine taking even just two or three of them in a single night! On the other hand, I'd think 1/20th of my pill (.5mg) would be way too little. After reading this relevant paraphrase from the article:

> There have been few studies on sighted young people. One finds that 1 mg works but 0.3 mg doesn’t; this study is an outlier. Another study on 25yo found both to work equally. Another study on 22-24yo found that 0.3 mg worked better than 1.0. UpToDate and Mayo Clinic suggests using at most .5mg. John Hopkins’ experts almost agree: they say “less is more” but recommend 1-3 mg.

I wonder if I should actually start cutting my pills in 20ths now... The author goes on to say he personally thinks that .3mg is a good amount and anything beyond 1mg is too much.

Edit: Sorry for the edits, I read the article after I made my comment, then figured I'd share their answer since I asked the question myself.


> On the other hand, I'd think 1/20th of my pill (.5mg) would be way too little.

That's one of the key points of the article:

> “But my local drugstore sells 10 mg pills! When I asked if they had anything lower, they looked through their stockroom and were eventually able to find 3 mg pills! And you’re saying the correct dose is a third of a milligram?!”

> Yes. Most existing melatonin tablets are around ten to thirty times the correct dose.


Yes, I ended up reading the article after commenting (shame on me) and edited my answer to contain their answer. Sorry!


Honestly for me the ideal dose is 250ug. I take half of a Trader Joe’s 500ug pill.

Melatonin has a U shaped dose curve so you either need a tiny bit or a whole lot to be effective.

500ug leaves me groggy in the morning, 250 is perfect.


Oddly enough, I've found that anything much over 1mg doesn't seem to have much of an effect at all - it maybe makes me a little drowsy, but that's about it. On the other hand, .5mg more or less knocks me out and leaves me feeling sleepy for most of the next day. Seems almost like there's a threshold over which it loses effectiveness, but I don't know of any medical mechanism that would lead to that.


I have been taking melatonin for a couple decades, due to severely delayed sleep. I haven't tried anything less than 3mg recently, but that has been very successful. 5mg or more have been too much, although I don't remember the specific problem.


3 mg is also the sweet spot for me. More than about 5 makes me have really wild, restless dreams. I still sleep feel rested in the morning, but it's kind of like you spend the whole night half awake because the dreams are so vivid.


It is strange. I take the Trader Joe’s brand as well and even half of a 500mcg pill is enough for me, and sometimes feels as effective as a a 3mg of 5mg pill from a different brand. Not sure what to make of it, other than maybe all I need is a placebo.


I've found the same thing.


Kroger sells 10 mg dissolvable tablets right now (and it's on sale!) - it definitely made me sleep but totally obliterated my metabolism when i was taking it. regulation is definitely needed


10mg?! Holy smokes, 3mg can turn me into a zombie the next day. Oh, I sleep well, but so do the undead.


It's rolling a 20 when you usually roll an 8. You successfully SLEEP, and there's a bonus!


At one point I was taking 40mg.


thanks - that was a typo.


Why are stock buybacks an ugly picture?


they aren't.

many fortune 500 companies offer some mechanism for employees to own stock, such as ESPP.


Lots of people already do that. You haven't discovered some secret strategy for getting into a US college.


Can you point me to cases of overtly White Europeans applying and being admitted to top programs as another race?



I have multiple classmates and relatives who proudly did this. Interestingly, all are conservative and anti-affirmative action. Their pride was probably related to exploiting the system or proving that it's poorly policed.


[flagged]


What? I don't pay attention to Trump's speeches, but my question was asking about acceptance to top programs as a different race. Not a politician elected who claimed partial racial heritage.

Can a White guy apply to the top CS program as a Black female, simply because he identifies as one? Where is the line drawn?


Except Elizabeth Warren had already taught at UPenn and other top schools and was already a well known figure in bankruptcy law...


"Pure acid" is a pretty meaningless description. Water is a weak acid (and also a weak base) so in a sense ordinary water could be described as "pure acid".


I don't think you are the only one. I imagine the courts would have the same opinion.


I would not consider it to be one. Nicotine is not the most harmful part of tobacco use, the smoke is.

Nicotine is a helpful drug that enhances focus and working memory. Forcing tobacco to be sold with lower nicotine content seems to be throwing out the baby, and keeping the bathwater. Completely the opposite of what is good.


Well you would be wrong.


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