Could be upsides to that, but cranking up the global food requirements (remember, a muscular body requires a lot more energy to maintain) would be a negative.
Also, what's optimal? Your body adapts to what you are doing, something we take for granted today. E.g. If you like bicycling, a permanent linebacker build may be undesirable.
It would probably be more ideal to set some kind of fitness "floor", rather than remove the mechanism completely.
Make your organism always maintain optimal muscles and circulation system while burning a lot of calories? Seems like a win/win to me.
Some people are strong and healthy without excersice, I think we are all entitled to same package?
I had PE in University (and before that school), hated it and now I'm turned off from any excercise.