On the other hand, (at least in the I, Robot stories) the Three Laws actually seem to be fine as a realistic/workable solution; all the conflict revolves around robots being programmed to not obey them, whether due to added rules before Rule 1, elided rules, or reordering of rules.

Prime-Directive-related conflicts, meanwhile, seem to revolve around cases where the Directive itself is flawed (or at the very least not ideal for a given situation).