Do you know much about nlrp3? I read an interesting paper by some investigators who later formed a company called inflazome, but am not sure how the biology or chemistry has evolved since then
It is getting more attention these days, and the older discoveries have had enough following attention to be fairly widely known in the field. It isn't a line of research I've followed specifically, but if you look at PubMed you can follow the trail over the past decade.
They have a histogram by year, and papers looking it over in the context of inflammation are getting quite common. I'd expect some sort of trial to emerge in the next few years, it seems to be getting to that point.
