Relationships; my wife, my child, my family, my friends, my employees, my peers and my bosses. I find all my real regrets and upsets stem from not doing these right, they all compete for time, but in the end they make the tapestry of your life.
I think this is the most sage advice of all. There's a TED talk that also says the same based on an extensive study: "What makes a good life?" https://www.youtube.com/watch?v=8KkKuTCFvzI