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Oh this is bloody awful:

> we developed a guinea pig model of tinnitus induced by noise exposure ...

> choosing a stimulus interval known to induce long-term depression (LTD). Twenty minutes per day of LTD-inducing bimodal (but not unimodal) stimulation reduced physiological and behavioral evidence of tinnitus in the guinea pigs

https://stm.sciencemag.org/content/10/422/eaal3175

I'm not anti-science and I understand the need for animal testing to reduce risks to humans but this raises serious ethical concerns where no such risk to humans exists.



But humans already testing on their own bodies: https://www.youtube.com/watch?v=MMzU66IHe-k


Why I enjoyed this more than I should have ?


It still doesn't even make sense. How does something that "induces long term depression" have a separate effect of "reduces evidence of tinnitus"?

Are they saying this stimulation that apparently cures tinnitus also causes depression?



Ok, TIL, I thought it was cronic depression. But still, I see no reason to risk causing actual cronic depression via repeated noise trauma.


It means "switch off the nerves", not "make them sad".


>I'm not anti-science and I understand the need for animal testing to reduce risks to humans but this raises serious ethical concerns where no such risk to humans exists.

What concerns? We already test on animals merely for cosmetics...


Cosmetics are potentially harmful to humans, and that harm can be prevented by testing on animals first.

Maybe there is some risk of this tinnitus treatment causing harm (could be something like https://en.wikipedia.org/wiki/Havana_syndrome), and animal testing would avoid that. But it's not necessary to inflict extra suffering to show that. Maybe they had to show the combination of the treatment with tinnitus doesn't cause harm but I doubt that.

There's also an argument where a disease is rare and inflicting animals with it to allows for efficacy testing, but tinnitus isn't rare, plenty of human volunteers are available. (I mean, half the people in this thread have already "volunteered" to perform testing of possible treatments on themselves, myself included).

Lastly as others have pointed out there are many causes of tinnitus. The researchers only inflicted one kind of it (I'd assume it's the same kind that everyone hears after hearing loud noises, since these guinea pigs were presumably otherwise healthy), it's possible this treatment only works on that kind and is a waste of time for everyone else.


>Cosmetics are potentially harmful to humans, and that harm can be prevented by testing on animals first.

I think the idea was "unless is needed to avoid harm" in general, not "unless is needed to avoid harm caused by people using a non-essential product".

E.g. curing cancer is OK, making BS products like cosmetics safer is pushing it as a justification (since those could just, like, not be made in the first place).


I don't think you've understood my point. I agree that cosmetics testing on animals is cruel, but it does serve a purpose, it doesn't matter how fucking selfish that purpose is, my point is that purpose exists.

What is the purpose of inflicting tinnitus on animals?




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