Does "motherboard" even make sense as a term? It's not like a motherboard gives birth to little baby boards that eventually grow up to be mother and father boards of their own. It's just one of those weird words we accept because it's been part of a shared vocabulary for so long. I don't particularly see any harm in assigning a gender role to a hardware device, but I don't see anything is particularly gained either. "Mainboard" is fine.
I'm fairly sure that "motherboard" came about as a term specifically for computer logic boards with slots that other cards -- "daughterboards" -- plugged into. It's very much from the 1970s era when we referred to "microcomputers", "minicomputers" and "mainframes". Granted, I'm a Mac user -- the last time I bought a "motherboard", I think it was a Pentium 4 -- and we tend to use the phrase "logic board" over here in Apple land, probably because, other than debatably the Mac Pro, we haven't had motherboards using the canonical definition for a very long time.
At any rate, while I wouldn't go out of my way to squelch the word, I wouldn't go out of my way to insist on it, either. "Logic board" and "mainboard" both work and get the point across.
