Yeah, it's all about your threat model. If I was a whistleblower against the US government, Kaspersky would be at the top of my list of "most trustworthy antivirus software". But if you're developing missile defense systems for the US, not so much.
Who do you fear most, and who is able to protect you from those people? Sadly there are preciously few neutral parties who'd protect you from everyone, so you have to choose your poison.
This is why I tend to not use an Antivirus at all. Kinda stupid, sorta... but you can't have a man in the middle attack occur of any sort; if you don't have any men in the middle...
Who do you fear most, and who is able to protect you from those people? Sadly there are preciously few neutral parties who'd protect you from everyone, so you have to choose your poison.