Do you look at every 'awesome list of JS frameworks' or whatever and assume everyone else looking at it is shipping some insane Frankenstein's app that uses every single one?

The point of it is just a list of suggestions, use none even, just ideas/inspiration for what you might want to ask. As someone who can never think of any questions in the moment (and interviewers have seemed to think that's not a good sign in the past, small sample size though and I may be misreading), I appreciate it.

Usually it's 3 questions per interviewer with 6 rounds that comes out to around 20 questions. I think a list of 251 to choose from is pretty fair in that regard.