It is an amazing book, not just for science fiction fans. The first story, "Tower of Babylon" somehow is like a science fiction story but based on ancient people's cosmology. Great book.
The stories are insanely creative and leave you thinking: Hell is the absence of God is a fantastic genre-bender I can imagine few other authors writing. Exhalation is also great, but it's in a different anthology.
Best story in the book, imo. The first and last story (about the angels) are the best. I was a little underwhelmed by _Story Of Your Life_ and _Understand_, given their reputation.