How did you make that connection? I didn't get that info from this study, but I have seen other studies that suggest sleep deprivation causes neuroinflammation, and I have seen studies that say coffee can reduce neuroinflammation. I have seen that the neuroinflammation described as a defense mechanism to assist with the removal of toxins. Possible connection being that if coffee reduces neuroinflammation when there are toxins present that may be a cause for more damage? I have zero qualifications, just trying to understand.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658704/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476750/