It’s relieving that at least other branches of vaccine development are not under the information regime as with COVID.
“However, environmental bacteria complicate the picture. If present before vaccination, memory immune cells primed to destroy the environmental relatives might cross-react with and neutralize the BCG strain before it has a chance to set up an immune response against itself and M. tuberculosis.”
Nobody cared if one already had covid before administering the vaccine and since the vaccine came late many have had a previous infection already. The new mRNA vaccine utilities the body to produce the actual pathogen and with already existing immunity from a previous infection one’s immune system starts to attack the mRNA modified cells and pathogen product.
Previous COVID infection enhances immunity, creating what we call hybrid immunity. This happens because current vaccines mainly target the spike protein, while natural infection exposes the immune system to other parts of the virus.
New vaccines in development aim to include multiple proteins and improved delivery methods, which could lead to longer-lasting immunity. For now, hybrid immunity (infection plus vaccination) offers broader protection, while vaccines safely boost antibody levels without the risks of infection.
An infection exposes the immune system to the whole virus while the mRNA vaccine triggers the synthesis of the viral spike protein which would be a specific part of the virus. It can be called hybrid since it is a combination of a original and novel technique but the underlying immune system still deals with the invaders the same way and creates immunity against them. Naturally an infection would be temporary but with the mRNA technique it's a constant stream of spikes which the immune system attacks to the source. One of the issues here are the byproducts from the immune activity, especially dangerous if the mRNA dosen't stay around the injection area. Hybrid immunity without looking at the cons is not the full picture and seeing some counterpoints about vaccines was refreshing.
“However, environmental bacteria complicate the picture. If present before vaccination, memory immune cells primed to destroy the environmental relatives might cross-react with and neutralize the BCG strain before it has a chance to set up an immune response against itself and M. tuberculosis.”
Nobody cared if one already had covid before administering the vaccine and since the vaccine came late many have had a previous infection already. The new mRNA vaccine utilities the body to produce the actual pathogen and with already existing immunity from a previous infection one’s immune system starts to attack the mRNA modified cells and pathogen product.