Prof. Sabine Hossenfelder is a pretty clear-headed communicator. I've been following her for nearly 20 years, almost since she started writing the Backreaction blog.
Her criticisms boil down to:
1. Modern science spends perhaps too much time on frivolous research that doesn't lead to anything. This very much applies to the theoretical physics and the endless series of attempts at ToE. But it's not limited to theoretical physics.
2. Modern scientific communication is often misleading and exaggerated.
3. The internal workings of scientific institutions are broken.
The challenge is that she’s right on all three of these major points … to some extent. Unfortunately at times she seems eager to fling babies without even encountering bathwater.
You are making her arguments for her. We should not "boil down" the arguments she makes. This is some of the arguments she makes. She does not ground it in particular, measured criticisms, aimed at particular researchers or departments. She does not provide solutions. She uses this broadly sweeping argument as a way to cast judgment on fields of research she is not an expert in. We should evaluate the arguments that she makes, not the arguments we would like her to have made. This includes not just a dispassionate listing of the truth claims she makes, but the specific rhetoric she employs. Is modern science flawed? Absolutely. Should we be saying "scientists are not to be trusted" as a general, categorical statement? No, that's laughable, and dangerously anti-intellectual.
Her criticisms boil down to:
1. Modern science spends perhaps too much time on frivolous research that doesn't lead to anything. This very much applies to the theoretical physics and the endless series of attempts at ToE. But it's not limited to theoretical physics.
2. Modern scientific communication is often misleading and exaggerated.
3. The internal workings of scientific institutions are broken.