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As someone hoping to enter a systems metabolomics program next year, let me simplify your statement:

If you do this, you're messing with high-order, nonlinear dynamics.

Does anyone really trust themselves to dose that properly? They had better be a trained medicinal chemist with great skill at solving PDEs. I also doubt the average enthusiast is set up to run HPLC to measure and model various critical metabolite concentrations and their change over time.



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