Web development is quite a different beast. There’s huge amount of life and struggle in the ecosystem, but only a fraction of that pushes the platform forward. I am relieved every time I move from some web development work back to plain, sane Cocoa APIs.

Which toolsets do you feel are the most exemplary of this?

I'm not a developer, but I'm finding this conversation very interesting given the original concept for iPhone apps was to have web apps only.